2022 Ducati Panigale V4 S

The 2022 Ducati Panigale V4 S represents the premium tier of Ducati's superbike range, sitting above the base Panigale V4 as the marque's flagship track-focused machine. This is Bologna's answer to the question of how much performance can be packed into a street-legal motorcycle while maintaining some semblance of ridability.

The V4 S delivers its considerable power through Ducati's Desmosedici Stradale engine, a counter-rotating L-twin that pulls hard from mid-range through a screaming top end. The bike rewards aggressive riding with razor-sharp handling and sophisticated electronics that can flatter lesser riders while staying out of the way of expert pilots. On track days and canyon runs, it's surgical in its precision, though commuting will remind you this isn't built for comfort.

The 2022 model carried over without significant mechanical changes from the prior year — buyers comparing it to a 2021 example should focus on mileage, service history, and condition rather than spec differences.

This machine attracts serious track riders stepping up from 600cc bikes, experienced pilots replacing older superbikes, and collectors drawn to Ducati's racing pedigree. The 2022 Ducati Panigale V4 S commands strong resale values among enthusiasts who prioritize performance over practicality.